Text from the Plaque
Regiopolis College, incorporated March 4, 1837, by an Act of the legislature of Upper Canada, opened in the central portion of this building. Its corner-stone was laid by the school's founder, Bishop Alexander Macdonell, on June 11, 1839. In 1866 the College was given full degree-granting powers, although these were rarely used. Financial difficulties forced its closing in 1869. In 1892 the building was acquired by the Religious Hospitallers of St. Joseph who opened here the Hôtel Dieu Hospital. The school reopened on King Street in 1896 and, in 1915, moved to the northern part of the city. In 1931 the diocesan clergy transferred the College to the Jesuit Order.
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